This is a loaded question. Often times what is appropriate will depend on the verbiage of the contract and determined on a case by case basis. We do have some general guidelines we like to start with:

Safety Items

We always recommend starting with items that could pose a safety risk. Things like high radon gas levels, electrical malfunctions, loose railings, fireplace/chimney safety items.

Reasonable Items

Active termites, hail damaged roof, plumbing systems not properly operating, HVAC to be working properly. These items are very typical and reasonable for a buyer to request. The above-mentioned items may require a second opinion from a qualified specialist in the appropriate field.

Typically Unreasonable Items

Asking for cosmetic and/or mechanical upgrades, pest control prevention systems, new paint and/or flooring and landscaping. Many of these items should have already been negotiated in the offer if they were a concern to the buyer. 

 The more realistic you keep the negotiations, the better the chances of a win-win solution for everyone. Luckily, you have a Realtor that will help guide you through the inspection negotiation process. Together we will determine what is and is not reasonable to ask for if you are a buyer and/or agree to repair if you are a seller.